{{sellerTotalView > 1 ? __("sellers", {number: sellerTotalView}) : __("seller", {number: sellerTotalView}) }}, {{numTotalView > 1 ? __("items", {number: numTotalView}) : __("item", {number: numTotalView}) }}
free FREE

Change Your Zip Code

Inventory information and delivery speeds may vary for different locations.

Location History

{{email ? __('Got it!') : __('Restock Alert')}}

We will notify you by email when the item back in stock.

Cancel
Yami

Jingdong book

产前诊断

{{buttonTypePin == 3 ? __("Scan to view more PinGo") : __("Scan to start")}}

产前诊断

{{__(":people-members", {'people': item.limit_people_count})}} {{ itemCurrency }}{{ item.valid_price }} {{ itemCurrency }}{{ item.invalid_price }} {{ itemDiscount }}
Ends in
{{ itemCurrency }}{{ item.valid_price }}
{{ itemCurrency }}{{ priceFormat(item.valid_price / item.bundle_specification) }}/{{ item.unit }}
{{ itemDiscount }}
{{ itemCurrency }}{{ item.valid_price }} {{ itemCurrency }}{{ priceFormat(item.valid_price / item.bundle_specification) }}/{{ item.unit }} {{ itemCurrency }}{{ item.invalid_price }} {{itemDiscount}}
{{ itemCurrency }}{{ item.valid_price }}
Sale ends in
Sale will starts after Sale ends in
{{ getSeckillDesc(item.seckill_data) }}
{{ __( "Pay with Gift Card to get sale price: :itemCurrency:price", { 'itemCurrency' : itemCurrency, 'price' : (item.giftcard_price ? priceFormat(item.giftcard_price) : '0.00') } ) }} ({{ itemCurrency }}{{ priceFormat(item.giftcard_price / item.bundle_specification) }}/{{ item.unit }}) Details
Best before

Currently unavailable.

We don't know when or if this item will be back in stock.

Unavailable in your area.
Sold Out

Details

Full product details
Content Description

《产前诊断》内容全面,包括了产前诊断、胎儿风险以及其他相关临床问题,主编和编者包括许多国家的著名专家。该书既阐述了经典的遗传学原则,又介绍了最新的诊断方法。此外,还详细介绍了可能会给胎儿的生长发育带来不利影响的各种危险因素、影像和其他诊断技术的新进展、按照系统排列的诊断、胎儿治疗、所有过程中的咨询,以及这些情况所带来的法律、伦理、跨文化甚至政治问题。
《产前诊断》的临床内容包括:
·遗传风险因素与风险评估
·产前遗传咨询
·环境因素、职业因素、病毒感染、细菌感染、放射因素等对胎儿的风险
·诊断方法。包括最新的影像学技术
·影像学技术的优点、缺点
·超声检查的全面讨论
·胎儿异常的分系统诊断
·350幅图片
·侵入性诊断和实验室诊断的最新进展
·胎儿异常的咨询
·胎儿异常的处理与治疗
·胎儿手术
·减胎术与终止妊娠
·经典遗传学、分子生物学、细胞遗传学的综述
·跨文化、法律、伦理问题的讨论
在胎儿风险的诊断、评估和处理方面,《产前诊断》较其他同类书更全面、权威,对于妇产科医生、住院医生以及其他孕前、孕期妇女保健医生来讲,是一本必读案头参考书。
Catalogue

第一部分 遗传学和生殖风险
第1章 经典遗传学原理
第2章 非整倍体的流行病学
第3章 遗传学新概念
第4章 染色体异常
第5章 产前诊断中的孟德尔遗传学
第6章 综合征:研究胎儿畸形的方法
第7章 基因与发育
第8章 产前遗传咨询
第9章 畸形学原理
第10章 药物
第11章 饮酒对孕期的影响
第12章 环境和职业对生殖和发育影响的评估
第13章 妊娠期细菌感染
第14章 病毒因素和生殖风险
第15章 妊娠期电离辐射暴露
第16章 妊娠期化疗

第二部分 超声诊断和筛查
第17章 胎儿全面超声检查:一种诊断和处理胎儿畸形的方法
第18章 胎儿脑图像
第19章 心血管畸形
第20章 胎儿腹部与腹壁正常和异常所见
第21章 泌尿生殖道畸形
第22章 胎儿骨骼发育不良
第23章 生化筛查
第24章 妊娠早期胎儿颈项透明层的超声筛查
第25章 妊娠中期非整倍体染色体异常的超声指标
第26章 先天性畸形的彩色多普勒
第27章 妊娠中期彩色多普勒和胎儿畸形
第28章 多胎妊娠的超声检查
第29章 三维超声在产前诊断中的应用
第30章 胎儿神经系统的三维超声
第31章 计算机和超声
第32章 胎龄确定和生长发育评估在产前诊断中的作用
第33章 胎盘的超声诊断

第三部分 操作
第34章 羊膜腔穿刺术
第35章 早期羊膜腔穿刺术:风险评估
第36章 绒毛取样
第37章 脐带穿刺术
第38章 组织活检
第39章 胎儿皮肤采样及重症遗传性皮肤病的产前诊断
第40章 手术性胎儿镜

第四部分 实验室诊断
第41章 细胞遗传学和分子细胞遗传学
第42章 生化遗传学
第43章 产前分子诊断学
第44章 分子筛查
第45章 使用来源于母血的胎儿细胞进行产前诊断
第46章 临床蛋白质组学

第五部分 问题处理
第47章 产前诊断和流产的心理学反应
第48章 胎儿异常的咨询
第49章 终止妊娠
第50章 胎儿尸检
第51章 多胎妊娠的减胎术
第52章 选择性终止妊娠
第53章 胎儿异常的产前处理
第54章 先天畸形新生儿的评估与处理

第六部分 胎儿治疗
第55章 胎儿分流手术
第56章 胎儿手术治疗先天性膈疝的演变过程
第57章 胎儿开放性手术:先天性囊性腺瘤样畸形
第58章 孟德尔遗传病的胎儿药物治疗
第59章 叶酸与神经管缺陷的预防
第60章 胎儿心血管系统评估
第61章 产前心脏治疗
第62章 胎儿基因治疗——体细胞
第63章 胎儿基因治疗——干细胞

第七部分 伦理、法律和社会问题
第64章 产前诊断中的社会心理问题
第65章 伦理和产前诊断:多文化交汇的影响
第66章 胎儿治疗学的伦理规范
第67章 基因诊断与遗传咨询的法律问题
第68章 政治与遗传生育风险
Book Abstract

人类中也有证据支持这一假说。正如Down综合征发生风险在女性30岁后呈指数增加,这也提示了30岁后可利用的卵泡数量呈指数下降。我们认为卵母细胞库损耗至某个阈值以下会触发生殖系统快速老化,最终表现为绝经。有两项研究报道绝经年龄提早与三体有关。其中的一项研究发现,生育Down综合征患儿后平均10.2年内发生绝经,而年龄匹配的对照组为12.8年。另一项研究发现,经生育年龄校正后,那些三体妊娠流产妇女的绝经平均年龄比染色体正常妊娠流产或活产的妇女早1年帅。实施单侧卵巢切除术后的妇女绝经年龄可能会提前,尽管这种影响不是很大。在一项病例一对照研究中发现外科切除或先天缺乏1个卵巢的妇女,其Down综合征妊娠风险增高9倍。有一组绝经期显著提前的妇女是有排卵功能的Turner综合征患者。文献(来自Tarani等的系统性回顾及Birkebaek等的最近的文献)已报道了221例这类妇女的怀孕情况,有4例是Down综合征患儿,发生率为1.8%,这类妇女Down综合征妊娠风险较正常人群高得多。
由于绝经期前后的时间很长,研究报道的绝经年龄有相当大的主观性,不是一个可靠的卵巢功能衰竭的检测指标。血清卵泡刺激素是一个更可靠的指标。有报道在那些以前生育过Down综合征患儿的妇女舛以及那些由于胎儿是非整倍体而早期流产的妇女中血清卵泡刺激素浓度升高。微循环受损假说
这一假说认为染色体不分离是由激素不平衡触发的一系列连锁事件造成。激素不平衡造成卵泡周围微血管系统处于非最佳状态,导致该区域内血流量下降。缺氧引起卵泡内二氧化碳和乳酸浓度增高,从而导致卵母细胞内pH值下降,这使有丝分裂纺锤体变小,继而发生染色体不分离。
虽然动物实验确实支持异常pH值导致染色体不分离,但这一假说的2个前提是矛盾的。首先,假说的拥护者引用母亲年龄效应的研究作为激素不平衡的证据,因为该研究中母亲年龄曲线看上去是J型的。他们认为这是由于初潮时相对高的发病率及接近绝经期时极度增高的发病率造成的。然而,正如我们上面显示的,母亲年龄曲线事实上并不是J型的。第二,受损的微循环与pH值下降之间的假设联系是卵泡内没有内循环,但是卵母细胞和精母细胞都与血管不直接接触,众所周知卵巢是血管最丰富的器官。
Introduction

这真是一本“大书”,无论是从厚度还是从覆盖的内容,都令人印象深刻!考虑到40年前,这只可能是很小的一本书,甚至是写不出什么内容。在那时候人类细胞遗传学才刚刚开始,直到1967年羊膜腔穿刺才开始被用于遗传性疾病的产前诊断,超声只是用于发现中线的偏移,还没有把胎儿作为病人进行讨论。然而40年以后,需要写68个章节来全面覆盖产前诊断及其相关内容。即使只是作为遗传学革命的一个部分,这已经是相当了不起的发展,医学领域的发展中只有很少一些内容能与之相比。
写一本这一领域的书需要一定的勇气,幸好有Mark。Evans,MD,在他1992年的那本书《生殖风险和产前诊断》的基础上进行了扩展,与他的3个学生一起完成了这个任务。这本书对这一领域来讲是一个很大的贡献,它告诉我们在这一领域的科学进展有多大。这些作者在各自的领域中都是非常了不起的权威,为读者呈现了整个产前诊断领域的现状。
.|ohn Fletchel-肯定会喜欢献给他的这本书,他的背景是神学,作为生物伦理学家(第一个),他在NIH的临床研究中心积累了无可比拟的经验,然后他又关注于生殖健康和母胎医学领域的生物伦理学问题,他在这一领域的发展和进步方面起了非常重要的作用。John.Fletcher·坚信,不仅仅好的伦理学是从好的科学开始的,而且做出一个正确的伦理学决定需要对科学和医学实践有很好的理解。他肯定会仔细阅读此书,几乎每一页都会提出新的伦理问题,需要仔细的考虑。随着他的注意力逐渐转移到产前诊断和妊娠期的决定选择,他提供了两个非常有价值的贡献。首先,他是这一领域的主持正义者,他不断提出尖锐的问题,问一些有时过于大胆的围产学者他们究竟在做什么?是如何做的?让大家明白母亲/孕妇是最终的做决定的人。他在这方面扮演的角色非常重要,可以帮助临床医生和研究者避免这一领域的许多潜在问题,本来这些努力是出于良好愿望的,但是如果不能够审慎处理,就会带来很坏的名声。其次,他是这一领域的倡导者,他指出为了做出正确的决定和行动,需要进行研究来获得相应的知识。他喜欢与科学家、医生、鼓吹者、政客就伦理问题进行争论,但是在开始之前他总是要确认自己理解科学。

Specifications

Brand Jingdong book
Brand Origin China

Disclaimer

Product packaging, specifications and price are subject to change without notice. All information about the products on our website is provided for information purposes only. Please always read labels, warnings and directions provided with the product before use.

View Full Terms of Use
Add to favorites
{{ $isZh ? coupon.coupon_name_sub : coupon.coupon_ename_sub | formatCurrency }}
{{__("Buy Directly")}} {{ itemCurrency }}{{ item.directly_price }}
Quantity
{{ quantity }}
{{ instockMsg }}
{{ limitText }}
{{buttonTypePin == 3 ? __("Scan to view more PinGo") : __("Scan to start")}}
Sold by JD@CHINA
Ship to
{{ __("Ship to United States only") }}
Free shipping over 69
Genuine guarantee

Added to Cart

Keep Shopping

More to Consider

{{ item.brand_name }}

{{ item.item_name }}

{{ item.currency }}{{ item.market_price }}

{{ item.currency }}{{ item.unit_price }}

{{ item.currency }}{{ item.unit_price }}

Coupons

{{ coupon.coupon_name_new | formatCurrency }}
Clip Clipped Over
{{ getCouponDescStr(coupon) }}
{{ coupon.use_time_desc }}
Expires soon {{ formatTime(coupon.use_end_time) }}

Share this item with friends

Cancel

Yami Gift Card

Get this exclusive deal when paying with gift card

Terms and Conditions

Gift card deals are special offers for selected products;

The gift card deals will automatically be activated if a customer uses gift card balance at check out and the balance is sufficient to pay for the total price of the shopping cart products with gift card deals;

You will not be able to activate the gift card deals if you choose other payment methods besides gift card. The products will be purchased at their normal prices;

If your account balance is not enough to pay for the products with gift card deals, you can choose to reload your gift card balance by clicking on the Reload button at either shopping cart page or check out page;

Products that have gift card deals can be recognized by a special symbol showing 'GC Deal';

For any additional questions or concerns, please contact our customer service;

Yamibuy reserves the right of final interpretation.

Sold by Yami

Service Guarantee

Yami Free Shipping over $49
Yami Easy Returns
Yami Ships from United States

Shipping

  • United States

    Standard Shipping is $5.99 (Excluding Alaska & Hawaii). Free on orders of $49 or more.

    Local Express is $5.99 (Available in Parts of CA, NJ, MA & PA). Free on orders of $49 or more.

    2-Day Express (Includes Alaska & Hawaii) starts at $19.99.

Return Policy

Yami is committed to provide our customers with a peace of mind when purchasing from us. Most items shipped from Yamibuy.com can be returned within 30 days of receipt of shipment (For Food, Beverages, Snacks, Dry Goods, Health supplements, Fresh Grocery and Perishables Goods, within 7 days of receipt of shipment due to damages or quality issues; To ensure that every customer receives safe and high-quality products, we do not provide refunds or returns for beauty products once they have been opened or used, except in the case of quality issues; Some products may have different policies or requirements associated with them, please see below for products under special categories, or contact Yami Customer Service for further assistance).
Thank you for your understanding and support.

Learn More

Sold by Yami

Terms and Conditions of Yami E-Gift Card

If you choose “Redeem automatically” as your delivery method, your gift card balance will be reload automatically after your order has been processed successfully;

If you choose “Send to Email”as your delivery method, the card number and CVV will be sent to the email address automatically;

Any user can use the card number and CVV to redeem the gift card, please keep your gift card information safely. If you have any trouble receiving email, please contact Yami customer service;

Yami gift card can be used to purchase both Yami owned or Marketplace products;

Yami gift card will never expire;

Yami gift card balance does not have to be used up at once;

All rights reserved by Yami.

Return Policy

Gift card that has already been consumed is non-refundable.

Sold by JD@CHINA

Service Guarantee

Yami Free Shipping over $49
Yami Easy Returns
Yami Ships from United States

Shipping

  • United States

    Standard Shipping is $5.99 (Excluding Alaska & Hawaii). Free on orders of $49 or more.

    Local Express is $5.99 (Available in Parts of CA, NJ, MA & PA). Free on orders of $49 or more.

    2-Day Express (Includes Alaska & Hawaii) starts at $19.99.

Return Policy

You may return product within 30 days upon receiving the product. Items returned must be new in it's original packing, including the original invoice for the purchase. Customer return product at their own expense.

Sold by JD@CHINA

Service Guarantee

Yami Cross-store Free Shipping over $69
Yami 30-days Return

Yami-China FC

Yami has a consolidation warehouse in China which collects multiple sellers’ packages and combines to one order. Our Yami consolidation warehouse will directly ship the packages to your door. Cross-store free shipping over $69.

Return Policy

You may return products within 30 days upon receiving the products. Sellers take responsibilities for any wrong shipment or missing items. Packing needs to be unopened for any other than quality issues return. We promise to pack carefully, but because goods are taking long journey to destinations, simple damages to packaging may occur. Any damages not causing internal goods quality problems are not allowed to return. If you open the package and any quality problem is found, please contact customer service within three days after receipt of goods.

Shipping Information

Yami Consolidation Service Shipping Fee $9.99(Free shipping over $69)

Sellers in China will ship their orders within 1-2 business days once the order is placed. Packages are sent to our consolidation warehouse in China and combined there. Our Yami consolidation warehouse will directly ship the packages to you via UPS. The average time for UPS to ship from China to the United States is about 10 working days and it can be traced using the tracking number. Due to the pandemic, the delivery time may be delayed by about 5 days. The package needs to be signed by the guest. If the receipt is not signed, the customer shall bear the risk of loss of the package.

Sold by JD@CHINA

Service Guarantee

Free shipping over 69
Genuine guarantee

Shipping

Yami Consolidated Shipping $9.99(Free shipping over $69)


Seller will ship the orders within 1-2 business days. The logistics time limit is expected to be 7-15 working days. In case of customs clearance, the delivery time will be extended by 3-7 days. The final receipt date is subject to the information of the postal company.

Yami Points information

All items are excluding from any promotion or points events on Yamibuy.com

Return Policy

You may return product within 30 days upon receiving the product. Items returned must be new in it's original packing, including the original invoice for the purchase. Customer return product at their own expense.

Yami

Download the Yami App

Back Top

Recommended for You

About the brand

Jingdong book

为您推荐

Yami
欣葉
2种选择
欣叶 御大福 芋头麻薯 180g

周销量 600+

$1.66 $1.99 83折
Yami
欣葉
2种选择
欣叶 御大福 芋头麻薯 180g

周销量 600+

$1.66 $1.99 83折
Yami
欣葉
2种选择
欣叶 御大福 芋头麻薯 180g

周销量 600+

$1.66 $1.99 83折
Yami
欣葉
2种选择
欣叶 御大福 芋头麻薯 180g

周销量 600+

$1.66 $1.99 83折
Yami
欣葉
2种选择
欣叶 御大福 芋头麻薯 180g

周销量 600+

$1.66 $1.99 83折
Yami
欣葉
2种选择
欣叶 御大福 芋头麻薯 180g

周销量 600+

$1.66 $1.99 83折

Reviews{{'('+ commentList.posts_count + ')'}}

Have your say. Be the first to help other guests.

Write a review
{{ totalRating }} Write a review
  • {{i}} star

    {{i}} stars

    {{ parseInt(commentRatingList[i]) }}%

Yami Yami
{{ comment.user_name }}

{{ showTranslate(comment) }}Show Less

{{ strLimit(comment,800) }}Show more

Show Original

{{ comment.content }}

Yami
Show All

{{ formatTime(comment.in_dtm) }} VERIFIED PURCHASE {{groupData}}

{{ comment.likes_count }} {{ comment.likes_count }} {{ comment.reply_count }} {{comment.in_user==uid ? __('Delete') : __('Report')}}
Yami Yami
{{ comment.user_name }}

{{ showTranslate(comment) }}Show Less

{{ strLimit(comment,800) }}Show more

Show Original

{{ comment.content }}

Yami
Show All

{{ formatTime(comment.in_dtm) }} VERIFIED PURCHASE {{groupData}}

{{ comment.likes_count }} {{ comment.likes_count }} {{ comment.reply_count }} {{comment.in_user==uid ? __('Delete') : __('Report')}}

No related comment~

Review

Yami Yami

{{ showTranslate(commentDetails) }}Show Less

{{ strLimit(commentDetails,800) }}Show more

Show Original

{{ commentDetails.content }}

Yami
Show All

{{ formatTime(commentDetails.in_dtm) }} VERIFIED PURCHASE {{groupData}}

{{ commentDetails.likes_count }} {{ commentDetails.likes_count }} {{ commentDetails.reply_count }} {{commentDetails.in_user==uid ? __('Delete') : __('Report')}}

Please write at least one word

Comments{{'(' + replyList.length + ')'}}

Yami Yami

{{ showTranslate(reply) }}Show Less

{{ strLimit(reply,800) }}Show more

Show Original

{{ reply.reply_content }}

{{ formatTime(reply.reply_in_dtm) }}

{{ reply.reply_likes_count }} {{ reply.reply_likes_count }} {{ reply.reply_reply_count }} {{reply.reply_in_user==uid ? __('Delete') : __('Report')}}

Please write at least one word

Cancel

That’s all the comments so far!

Write a review
How would you rate this item?

Please add your comment.

  • A nice nickname will make your comments more popular!
  • The nickname in your account will be changed to the same as here.
Thanks for your review
Our community rely on great reviews like yours to find the best of Asia.

Report

If you find this content inappropriate and think it should be removed from the Yami.com site, let us know please.

Cancel

Are you sure to delete your review?

Cancel

You’ve Recently Viewed

About the brand

Jingdong book