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[Yamimi Open Class | Live Content (3)] Moderate Moisturizing (Part 2)

【Yami Open Class|Live Content (3)】

Lesson 1: Moderate Moisturizing (Part 2)


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We have done these days What???

Before, we shared a lot of dry skin care products of [Yan An Tang] in the sun list

9From September 26th to September 29th, [Yan An Tang] was brought to the WeChat group of Yami Skin Care Open Class

1 hour a day The most scientific skin care basics

Full of dry goods

The editor of Yami will organize the content of the live broadcast and share it with those who are too late to listen to the live broadcast~


---The main topic is coming---



Looking at the left side of this picture, we can see that the human body is actually 70% water. If it is a A person of 100 pounds is equivalent to 70 pounds of water in the body. There is a data surface, the maximum amount of water a person can emit through the skin in a day is 10L! span>

Our keratinocytes are like a sink, it has a water inlet, that is, the water in the body will pass through the dermis to the keratinocytes At the same time, a large amount of water will flow out into the air.

So what we have to do is to maintain a dynamic balance. If the water in and out can be kept the same, our skin You can achieve normal moisturizing.



For skin, the water inlet is aquaporinAQP3, it stays under the epidermis (stratum corneum, basal layer, granular layer, all have this protein). The dermis has a lot of water (can reach hundreds of more than 80/80), this water slowly passes through the aquaporin and is transported up to the keratinocytes. This channel is unchanged.

There are two situations when water is replenished from outside the skin. One is that water penetrates into the skin. But the stratum corneum itself It is relatively resistant to water, so most of the water applied on the skin runs into the air, and only a small part can get into your skin.

Consider increasing the rate of water inflow. There are many products that claim to increase cellular aquaporin. However, , First, this is more difficult. The product must first pass through the barrier of the skin's stratum corneum and reach the cells below to function. Second, this will actually require a relatively high cost. Then, there is actually a more cost-effective method, that is Decrease the rate of water output.

Our skin thinks the same way. It has three gates at the water outlet to prevent the water from running too fast.

The first gate, there is a natural moisturizing factor NMF in our keratinocytes (Fig. The blue origin), it helps the cells catch water in the cell. The second gate is the lipids between cells (the light blue part), the familiar ceramides, cholesterol and free fatty acids. There is also a gate, It is the sebum secreted by the outermost sebaceous glands of the skin. Through the combined action of these three layers, the rate of water loss from the stratum corneum can be reduced.




The picture shows the composition of a natural moisturizing factor. It mainly contains a large number of amino acids,PCA, lactate urea, and sodium salt potassium salt and the like. Its effect is equivalent to turning the water inside the skin into saline, so the speed of water loss It will be slower than fresh water. The small water molecules in it can catch water, can also make water molecules run slower. However, this is not enough.



Even if it is saline, it will dry out if left in the sun. So it is necessary to fill the cells with lipids .

We often say that keratin is a city wall, a structure of bricks and cement. Bricks are keratinocytes, Cement is the lipid between cells. The lipid is mainly a combination of ceramides, free fatty acids and cholesterol.

Lipids must be stored in the basal cells and granular layer cells, and when the granular layer cells become keratinocytes, These lipids are spit out from the cells to coat the cells and help reduce water loss.


The interskin lipids have a very sophisticated structure and are difficult to replenish. span>

Substances such as ceramides are not only expensive, but also difficult to dissolve and further enter the skin. Some products have For such technology, for example, there are many ceramide products that can replenish the lipids between the skin and repair our skin barrier, which is very good. But there is a simpler and cruder method that we most commonly use, It is to work on the outermost layer.


In the outermost layer, the skin has sebum secreted by the sebaceous glands. p>

Sebaceous glands and hair follicles share the same outlet, which is our pores. It secretes sebum mainly including triglycerides, cholesterol, squalene and wax fat. Also, our sweat glands are another separate opening. Our sebum and sweat glands mix together to make up our sebum membrane, which forms our protective layer on the outside of our skin.


The normal skin moisturizing practice is to use oil on the skin. Creams and lotions will contain oil. However, in the end What is a good oil? Many people have the question, will using too much oil clog pores and cause blackheads and acne? The choice of oil should basically be in two directions.

First, the oil used is not friendly and incompatible with the sebum of the skin. It will not enter the skin if it stays outside. Hair follicles block pores.

This kind of grease, such as silicone oil, mineral oil. People will be more repulsive to chemical things, but in fact it depends on the actual situation Situation. Oils such as silicone oil or mineral oil are not friendly to sebum, they can act as a good seal on the outside of the skin and keep water out. At the same time, they are not easy to penetrate into the skin and make the skin feel uncomfortable.


The second type of oil, it is very friendly to your sebum and will not cause all kinds of irritation or blockage.< span>

For example, squalene and wax grease unique to our cortical membrane, many products like to use this kind of grease. Squalane can be turned into squalene on the skin, which is the same ingredient as the cortex. Wax is rarely found in nature. Here we should mention jojoba oil, which is very similar in structure to wax and can be very good. Penetrates well into the skin without irritating the skin.

 

Other oils like isopropyl palmitate, isopropyl myristate. They have some affinity with sebum, so It is easy to get into the pores of the skin. But they are not exactly the same structure as the sebum of the skin, so that the skin may not recognize them after entering. At this time, the pores will lose their temper, causing acne, fans and the like. Of course , it also depends on the amount of these oils contained in the product. If it is a small amount, it may not necessarily cause problems. Moreover, the occurrence of these conditions varies from person to person, and more often you have to try it yourself. span>

 

Finally, let’s talk about natural oils.

Although these oils have different names, they are actually relatives. They are all fatty acid glycerides, but the fatty acids in them The ratio is different.

Coconut oil is a skin care oil that is often mentioned. It can be seen from the table that it contains high lauric acid. Lauric acid is the kind of thing I just mentioned that likes to drill into the pores. Therefore, coconut oil may cause closure and acne in some people, and it is not a good skin care oil.

And then like olive oil, it has a lot of unsaturated fatty acids (such as oleic acid, linoleic acid, linolenic acid), which can Antioxidant. However, it also has a high content of oleic acid. Oleic acid likes to drill into the lipids between skin cells, which is the structure formed by the ceramides, cholesterol and free fatty acids we mentioned earlier. It is neat and can block the water. At this time, the oleic acid drills in and disperses the formation, and the water takes the opportunity to run away. Therefore, the high content of olive oil will weaken the skin barrier, and it is not a particularly good skin care. Oil.

 

You can use oils like rosehip oil and grapeseed oil on the skin, but better The method is to eat it in. Because the production of lipids between the skin requires the participation of unsaturated fatty acids necessary for the human body, that is, linoleic acid and linolenic acid. The source of these raw materials is mainly what we usually eat. After we eat it, blood vessels Send it to the dermis, and then from the dermis to the epidermis to supply epidermal cells to make ceramide.

 

The above is mainly about moisturizing the skin. In general, you can use water to supplement the outermost part, But the supplementation effect will be very weak. Now the lotion we use mainly does not rely on water, it contains a lot of glycerin, butanediol or even a lot of small molecules (such as NMF natural moisturizing factor). These Substances burrow into keratinocytes to help hold water molecules. Creams or lotions rely mainly on the oils in them.


In addition, there is a very commonly used moisturizing method - applying mask. 0 span0

The mask has the function of encapsulation, making it difficult for water to run into the air and promoting the running of water into the skin. This is true Very effective. So applying a mask usually has an immediate effect.

The keratinocytes become transparent after being absorbed, the skin becomes very bright, and people also appear white. However, using Masks also have problems. We mentioned earlier that if you soak your hands in blisters for a long time, you will wrinkle. If you keep applying the mask, too much water will suck up the keratinocytes that were originally shrewd and dry, causing them to not be able to stand guard for the skin. The permeability increases, and various pollutants in the air can easily enter. Therefore, the mask cannot be applied every day. In medical dermatology, there is a term called hydration dermatitis. It means that the skin absorbs too much water and the entire barrier function is lost. 。 At this time, external stimulation will lead to dermatitis.

 

In addition, it should be noted that other products, especially functional things, should be Be careful.

After applying the mask, everyone will want to take a strong medicine, such as high concentrationVC, retinol or retinol and other products. At this time, a large number of ingredients pour in, which may be harmful to the skin. Causes irritation and leads to allergies.

There is also makeup. After applying the mask to the skin, everyone will feel that the makeup is much easier to put on, and it is not easy to take off. However, If you put on makeup at this time, cosmetics (that is, make-up) are relatively more irritating than skin care products. Therefore, it is not recommended to put on makeup immediately after making the mask.

After applying the mask to open the moisture channel, it is best to close the door as soon as possible. At this time, you should use some comparison Basic moisturizing products. Skin care products such as creams are more suitable at this time.

 

Another misunderstanding that everyone may have, many people think that the external humidity of the skin is relatively high in summer, just use a little water However, everyone must remember the three gates of skin moisturizing. Of course, the water you use contains substances such as glycerin and moisturizing factors. But this alone is not enough. Even in summer, it is recommended that you use some oils. You can choose some The light lotion acts as an envelope on the outside of the skin for better hydration.


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【亚米公开课|直播内容(三)】之适度保湿(下)

【亚米公开课|直播内容(三)】

第一课之 适度保湿 (下)


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这几天我们做了什么???

之前我们在晒单中分享了【言安堂】大量的护肤干货

9月26日-9月29日【言安堂】在 亚米护肤公开课 微信群中带来

每日1小时 最科学的护肤基础知识

干货满满

亚米小编将陆续整理直播的内容分享给来不及听直播的各位~


---正题来了---



看这张图的左边,我们可以看到人体其实百分之七十都是水。如果是一个一百斤的人,相当于体内有七十斤的水。而有一个数据表面,人一天通过皮肤散发的水分最多可以到10L

我们的角质细胞就像水槽一样,它有进水口,就是身体里的水分会通过真皮层给角质层细胞补水。同时,也会有大量的水外流到空气中。

所以我们要做的事情就是保持一个动态的平衡。如果进水和出水能够保持一样,我们的皮肤就可以做到正常的保湿。



对皮肤来说,进水口是水通道蛋白AQP3,它呆在表皮层底下(角质层、基层、颗粒层,都有这个蛋白)。真皮层有非常多的水(可以到百分之八十以上),这个水慢慢地通过水通道蛋白,往上输送给角质细胞。这个通道是不变的。

而从皮肤外补水,会有两种情况。一是水往皮肤里面钻。但角质层本身就对水比较抗拒,所以绝大部分敷在皮肤上的水都跑到了空气里,只有很少一部分可以到你的皮肤里。

考虑到增加进水的速度这条路。有很多产品会宣称,增加细胞的水通道蛋白。然而,第一这比较难。产品首先要穿过皮肤角质层的屏障,到达下面的细胞才能作用。第二,这个事实上会需要比较高的成本。那么,其实有一个更有性价比的方法,就是降低出水的速度。

我们的皮肤也是这样想的。它在出水口设计了三个闸门来防止水跑得太快。

第一道闸门,我们的角质细胞内有天然保湿因子NMF(图中为蓝色原点),它在细胞里帮助细胞抓水。第二道闸门是细胞之间的脂质(浅蓝色部分),大家熟悉的神经酰胺、胆固醇和游离脂肪酸。还有个大闸,就是最外面的皮肤皮脂腺分泌的皮脂。通过这三层共同作用,能够降低角质层往外失水的速度。




图中是一个天然保湿因子的组成。它里面主要有大量的氨基酸、PCA、乳酸尿素,还有钠盐钾盐之类东西。它的作用相当于把皮肤内部的水变成盐水,这样失水的速度会相较淡水变慢。其中的清水性小分子可以抓水,也能让水分子跑的慢一点。但是,这还是不够的。



即使是盐水,放在外面晒也会被晒干。所以还要在细胞之间填充上脂质。

我们经常说角质是一个城墙,是砖块和水泥的一个结构。砖块就是一个个角质细胞,而水泥就是细胞间的脂质。脂质主要是神经酰胺、游离脂肪酸和胆固醇的组合。

脂质先要在基层细胞和颗粒层细胞储备好,等到颗粒层细胞变成角质细胞的时候,这些脂质就会从细胞里被吐出来包裹住细胞,帮助减少水分的散失。


皮肤间脂质有很精密的结构,补充起来也比较困难。

神经酰胺之类的物质不仅价格高,同时也很难溶解后进一步进入到皮肤。有些产品是有这样的技术的,比如说有很多神经酰胺产品可以做到补充皮肤间的脂质,对我们的皮肤屏障进行修复,这是非常好的。但我们最常见的还有个更简单粗暴的方法,就是在最外层下功夫。


在最外层,皮肤有着皮脂腺分泌的皮脂。

皮脂腺和毛囊共用一个出口,就是我们的毛孔。它分泌出来皮脂主要包括,甘油三酯、胆固醇、角鲨烯和蜡脂等。此外,我们的汗腺则是另一个单独的开口。我们的皮脂和汗腺分泌的汗水混合在一起,共同构成了我们的皮脂膜,它在皮肤外面形成了我们的保护层。


一般正常皮肤保湿做法就是在皮肤上用油脂。膏霜、乳液里面都会有油脂的成分。然而到底什么样是比较好的油脂呢?很多人会有这样的疑问,油脂用多了是不是会堵塞住毛孔,引起黑头、粉刺的情况?对于油脂的选择,基本上应该是两个方向。

一是使用的油脂跟皮肤的皮脂根本不友好、不亲和。呆在皮肤外面不会进到毛囊堵住毛孔。

这种油脂,比如硅油、矿物油。大家对化学的东西会比较排斥,但其实要根据实际的情况。硅油或矿物油之类的油脂和皮脂并不亲和,它们可以在皮肤外起到很好的封闭作用,把水挡住。同时,它们也不容易渗透到皮肤里,让皮肤感到难受。


第二类油脂,它跟你的皮脂非常亲和,也不会引起各种刺激或者堵塞。

比如我们皮质膜里特有的角鲨烯和蜡脂,很多产品都喜欢用这类的油脂。角鲨烷可以在皮肤上变成角鲨烯,也就是跟皮质是一样的成分。蜡脂这个成分天然很少存在。这里要提到霍霍巴油,它和蜡脂的结构非常像,可以很好地渗透到皮肤里,同时又不会刺激皮肤。

 

另外的油脂比如棕榈酸异丙酯、肉豆蔻酸异丙酯。它们跟皮脂有一些亲和力,所以容易进到皮肤的毛孔里。但它们跟皮肤的皮脂的结构又不是一模一样的,以至于进去之后可能皮肤并不认它们。这时毛孔就会发脾气,引起痤疮、粉丝之类的东西。当然,也要看产品中所含这些油脂的量,如果是少量也不一定会引起问题。而且,这些状况的发生是因人而异的,更多时候要靠自己去试。

 

最后讲一下天然的油脂。

这些油脂虽然名字不同,其实都是亲戚。它们都是脂肪酸甘油酯的结构,只不过里面脂肪酸的配比不同。

椰子油是经常提到的护肤油脂,从表里可以看到,它含有很高的月桂酸。月桂酸就是刚才说到的喜欢往毛孔里面钻的一类东西。所以,椰子油可能会导致一部分人的闭口、粉刺,并不是很好的护肤油。

然后像橄榄油,它有很多不饱和脂肪酸(比如油酸,亚油酸,亚麻酸),可以抗氧化。然而,它也有很高含量的油酸。油酸喜欢往皮肤细胞间的脂质里钻,就是我们前面说的神经酰胺、胆固醇和游离脂肪酸形成的那个结构。大家原本排队排得很整齐,可以把水挡住。这时,油酸往里钻把队形搞散了,水就趁机跑了。所以高含量的橄榄油,反而会让皮肤屏障被削弱,也不是一个特别好的护肤油。

 

对于玫瑰果油和葡萄籽油之类的油脂,你可以用在皮肤上,但其实更好的方法是吃进去。因为皮肤间脂质的制造需要有人体必须的不饱和脂肪酸,就是亚油酸和亚麻酸的参与。这些原料的来源主要是我们平时所吃的东西。我们吃进去以后,血管把它送到真皮层,再从真皮层送到表皮层,供给表皮细胞制造神经酰胺。

 

上面主要讲的都是皮肤保湿。总的来说,你可以通过用水,在最外面做补充,但是补充效果会很弱。现在我们用的化妆水主要靠的不是水,它里面有很多甘油、丁二醇或者甚至是很多小分子(比如NMF天然保湿因子)。这些物质会往角质细胞里钻,帮助拉住水分子。膏霜或者乳液主要则是靠它们里面的油脂。


除此之外,还有一个大家非常常用的补水保湿方法——敷面膜。

面膜有包封的作用,让水很难往空气跑而促进水往皮肤里跑。这样确实是很有效的。所以敷面膜通常有立竿见影的效果。

角质细胞吸饱以后变得通透,皮肤就变得非常亮,人也会显得白。但是使用面膜也有要注意问题。我们前面说到手泡水泡久了会皱。如果一直敷面膜,水太多了便会把原本精明强干的角质细胞吸撑,导致它没法好好得为皮肤站岗。皮肤的通透性增加了,各种空气中的污染物质都会容易进入。所以面膜不能天天敷。医学上皮肤科里有一个术语叫水合性皮炎。就是皮肤吸了太多的水,整个屏障功能就失去了。这时受到外界刺激便会导致皮肤炎。

 

此外,还需注意的是,面膜敷完以后对于其它的产品,特别是功能性的东西,要小心。

大家敷完面膜之后,都会想上一个猛药,比如去用高浓度VC、维A醇或者视黄醇之类的产品。这时大量成分涌进来,很有可能对皮肤引起刺激,导致过敏。

还有化妆,敷完面膜皮肤之后大家会觉得上妆容易许多,也不容易脱妆。但是,如果这时候化妆,化妆品(即彩妆)的刺激性相对比护肤品更大。所以,做好面膜以后不建议马上化妆。

敷完面膜把水分通道打开之后,最好是赶快把这门关上。这时,应该用一些比较基础的保湿产品。比如膏霜一类的护肤产品这时候用是比较合适的。

 

另外一个大家可能存在的误区,有很多人觉得夏天皮肤外湿度比较高,只要用一点水就够了。然而,大家要记得皮肤保湿的三道闸门。你们用的水中当然有甘油、保湿因子一类的物质。但是光靠这个是不够的,即使是夏天也建议大家用一些油脂。可以选择一些轻薄的乳液在皮肤外面起一个包封的作用,更好得做到保湿。


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