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Jingdong book

前列腺癌100问(第2版)

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《前列腺癌100问(第2版)》基于当前的医疗水平,结合医生的经验和患者的经历,阐释了前列腺癌筛查、诊断、治疗等方面的知识。希望《前列腺癌100问(第2版)》能够帮助您理解在前列腺癌的诊断和治疗过程中可能会面临的问题,解答你的困惑,为您治疗方案的选择提供一定的依据。
《前列腺癌100问(第2版)》共分七个部分。第一部分讲解前列腺的解剖和功能、前列腺疾病的先兆症状。第二部分至第四部分讲述前列腺癌的危险因素、筛查、诊断和分期。第五部分主要讨论前列腺癌治疗方案的选择。第六部分阐述因治疗前列腺癌可能引起的包括骨痛、尿失禁和勃起功能障碍等并发症的治疗。第七部分重点阐释前列腺癌患者在诊断、治疗和并发症方面经常遇到的一些问题。
Author Description

Pamela Ellsworth,医学博士,布朗大学泌尿外科、外科及儿科副教授。她主编了多部著作如Little Black Book of Urology,膀胱癌100问,勃起功能障碍100 问,过度活动膀胱和尿失禁100问,同时参编许多著作,担任多部杂志的审稿人。足迹遍布世界各地,所做讲座涉及泌尿外科多个方面。在这部前列腺癌100问第二版中,Ellsworth医师希望能为前列腺癌患者及其家人、亲友的问题和担心作详细解答,正如她说:“如果我能够让前列腺癌患者更了解这个疾病,能更好地进行诊断和治疗,那么我的目的就达到了。”
Catalogue

第一部分 基础知识
描述前列腺的解剖特点及功能,介绍前列腺特异性抗原检测,并讨论前列腺癌的一些征象
1.什么是前列腺,有什么作用?
2.女性是否有前列腺?女性体内能否测到前列腺特异性抗原(PSA)?
3.前列腺增大会出现哪些征象和症状?
4.前列腺特异性抗原(PSA)是什么?正常值为多少?
5.什么是游离前列腺特异性抗原(游离PSA)与总前列腺特异性抗原(总PSA)比值?
6.哪些因素会引起前列腺特异性抗原(PSA)值升高?
7.药物会影响前列腺特异性抗原(PSA)水平吗?雄激素治疗会引起前列腺特异性抗原(PSA)增高吗?
8.如果我在接受雄激素治疗,应该注意什么?
9.我可以在任何医院检测前列腺特异性抗原(PSA)值吗?
10.前列腺癌还有其他肿瘤标志物吗?

第二部分 前列腺癌
描述什么是前列腺癌及前列腺癌的高危人群
11.什么是前列腺癌?
12.前列腺癌的发病率如何?
13.前列腺癌有哪些高危因素?有哪些高发人群?是否有办法降低前列腺癌的发生率?
14.如果家庭成员里有前列腺癌患者,我得前列腺癌的风险高吗?
15.我是前列腺癌患者,我儿子得前列腺癌的风险高吗?他们应该什么时候开始进行筛查?
16.有能增加前列腺癌发病风险的基因吗?
17.饮食对患前列腺癌的风险会产生怎样的影响?
18.非裔美国人患前列腺癌的风险更大吗?
19.前列腺癌有哪些征象?
20.前列腺癌的病因有哪些?
21.哪些因素会导致前列腺癌的生长?
22.前列腺癌会转移到哪些部位?
23.先前行经尿道前列腺切除术未发现癌细胞,是不是意味着我现在没有,将来也不会患前列腺癌?

第三部分 前列腺癌的诊断
讨论如何筛查并检测前列腺癌
24.如何发现前列腺癌?
25.什么是前列腺癌筛查?
26.我的医疗保险包含前列腺癌的筛查和治疗吗?
27.为什么一些社区医疗机构不鼓励或不提及前列腺癌筛查?
28.什么时候我需要开始警惕前列腺癌?
29.何时终止前列腺癌筛查?
30.什么是直肠指检?由谁来做?
31.我直肠被切除了,如何进行前列腺检查?
32.什么是前列腺结节?
33.血清前列腺特异性抗原(PSA)异常与直肠指检异常结果肯定一致吗?
34.如果我的血清前列腺特异性抗原(PSA)高于正常值,是否立即进行前列腺穿刺活检?
35.经直肠超声引导下前列腺穿刺活检如何进行?
36.谁来明确前列腺癌的诊断?
37.病理科医生有可能做出错误的诊断吗?
38.何为Gleason评分?
39.我最近刚做过前列腺穿刺活检未发现癌细胞,但是发现前列腺上皮内瘤变(PIN),医生告诉我需要再次穿刺活检。什么是前列腺上皮内瘤变(PIN)?为什么我需要再次穿刺活检?什么是疑为前列腺癌的不典型腺体,是不是需要重复穿刺?
……

第四部分 前列腺癌的分期
第五部分 前列腺癌的治疗
第六部分 治疗的并发症
第七部分 前列腺癌的社会效应
词汇表
Book Abstract

医生会根据淋巴结是否有肿瘤受累来决定是否行前列腺根治性切除。如果淋巴结中只找到了很少量的肿瘤,有些医生仍会选择行前列腺根治性切除,另一些医生持反对意见。送检的标本将进一步固定处理做成永久的切片并再次进行病理检查。大多数情况下,永久切片和冷冻切片的病理结果是符合的。经会阴前列腺切除术的会阴切口无法切除盆腔的淋巴结,因此还需要做个独立的腹部正中切口或通过腹腔镜的方式切除盆腔淋巴结。对于选择行粒子植入疗法或近距离放疗的患者,需在治疗前取脐下腹正中切口或通过腹腔镜进行盆腔淋巴结切除。
对于高危患者应该切除盆腔淋巴结,因为它直接关系到治疗方式的选择。盆腔淋巴结阳性的比例与前列腺癌分期、PSA水平和Gleason评分密切相关。5%~12%的临床上认为是局限性前列腺癌的患者,术后被证实有盆腔淋巴结转移。因此,在行盆腔淋巴结切除前,应与手术医生讨论如果盆腔淋巴结阳性的话,下一步准备采取什么治疗方案。
盆腔淋巴结切除术的主要风险包括:出血,神经损伤,淋巴囊肿。
(1)出血 该术中切除的盆腔淋巴结位于一些较粗大的盆腔血管周围,如髂动静脉周围。损伤了髂血管或者其分支可能造成出血,但极少会出现大量出血甚至需要输血的情况。
(2)神经损伤 部分盆腔淋巴结包绕在支配腿部肌肉的闭孔神经周围。如果闭孔神经被切断或损伤但术中能及时发现,只要将其吻合即可,术后对下肢功能影响较小。如果术中未能及时发现,将有可能导致发生损伤的那侧下肢的活动受到一定程度的影响。
(3)淋巴囊肿 淋巴囊肿是由于淋巴管损伤造成淋巴液在盆腔积聚而形成。淋巴结被切除时,采用夹闭、结扎、烧灼淋巴管的方法均可减少淋巴漏的发生。淋巴囊肿一般不易察觉,也不会有什么大的危害。但是当体积增到一定程度时,可以压迫周围组织造成腹压升高或腹部疼痛。如果继发感染,可表现为高热、寒战以及腹痛。
……

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