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Jingdong book

复活猛犸象——一个古DNA科学家的探索

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Jingdong book

复活猛犸象——一个古DNA科学家的探索

Name: 复活猛犸象——一个古DNA科学家的探索
Brand: Jingdong book
SKU: 3137000071
Price: 42.78 USD
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Editer Recommend

《复活猛犸象》（How to Clone a Mammoth）把“灭绝生物复活”这个极具科幻色彩的题目转为科学家认真探讨的课题，由此借鉴了生命科学前沿领域诸多进展与成果，展现了在北极圈冻土带发掘猛犸象等灭绝动物遗骸的科考旅程，也介绍了世界基因工程实验室里的新探索，并讨论了通过复活灭绝生物性状来保护生物多样性的新途径。以这样的方式，本书传播了丰富的生命科学知识，也传递了科学改变世界的创新精神。

Content Description

本书作者以一位古DNA研究者和生命科学家的角色定位，讨论了使猛犸象等灭绝生物复活的可能性及生态意义。不同于《侏罗纪公园》的科幻题材，作者及其同行们摸索一条通过古DNA测序和基因工程来复活灭绝生物性状，从而改善生态的途径。在展示这个设想的过程中讲述了包括野外考察、基因技术、生物保护、生态重建与生态法规以及生命伦理在内的丰富知识。字里行间显露出科学探索者锐意进取和求真务实之精神风貌。

Author Description

作者贝丝·夏匹罗（Beth Shapiro），美国进化分子生物学家，1976年生于宾夕法尼亚州艾伦镇。她是加州大学圣克鲁兹分校副教授，专业从事古DNA的研究分析，有论著多种，文章见于英国《自然》和美国《科学》周刊。2009年获麦卡瑟天才奖（MacArthur Fellowship）。译者夏季：本名夏志，生于1984年，科普专栏作家和翻译者。曾留美攻读生物医学博士学位，现供职于某大型跨国企业。已出版书籍近十部，并获全国优秀科普作品奖、广东省科普作品创作大赛冠军等多项荣誉。

Catalogue

目录序一1
序二3
序三让思想飞向未来的窗口5前言1第一章逆转灭绝1
第二章选定一个物种16
第三章找寻完好标本47
第四章创造一个克隆67
第五章逆向选育91
第六章重建基因组100
第七章重构部分基因组115
第八章再造克隆130
第九章多多益善147第十章放“象”归山161
第十一章反思174致谢192
索引194
译后记202

Introduction

如何复活业已灭绝的生物，一直以来都是从事生物学研究的科学家们所亟待攻关解决的重大课题。它是那么地引人入胜，那么地令人心生向往。
然而一直以来，技术的障碍一再打击着科学家们那激动而澎湃的心，由技术瓶颈本身所引发出来的相关生态及伦理问题等更是一度甚嚣尘上。
不过，本书作者、古DNA研究领域的国际先锋——夏匹罗(Beth Shapiro)却是一位不畏艰苦的迎难而上者。她有着过人的勇气和魅力，试图通过精妙的阐述、细致的描写，化解纷繁复杂的内容，将高深的知识摊开来呈现给普通大众。她努力让微妙得甚至有点玄乎的复活项目变得真实而亲近。这本书告诉了我们什么是可能的，什么是不可能的，什么是有可能变得可能的，什么是不可能但可以变为可能的……总之，一切关于复活猛犸象的方方面面、林林总总、边边角角，似乎都已经囊括进此书中。它也摈弃了一味地说教，取而代之的是用耐心解释及广征博引，娓娓道出深埋其下的缘由。
的确，她成功地做到了！
说起来，这样好的科学家加好的写作者，确是罕见。作者用她有强烈意见的立场，为读者拓开了一种亲切的教育形式，把基因组技术中相当神秘的细节用温柔的言语描述出来，通过明晰而细致的措辞和读者喜闻乐见的形式把一个个难点解说清楚。无疑，在讲解逆转灭绝(deextinction)方面她是做得最到位的。她并非用局外人的角度或记者的姿态来写作，而是以一个对新领域本身有着深厚功底的科学家的眼光来看待这个领域。哪怕看似不经意的套语，也无不反映出她的细心琢磨与深思熟虑。
此外，作者的叙事手法活泼生动并富于幽默感，的确值得称道。以强大的科学知识储备作为后台，加以优美的文笔，两者之间所发生的“化学反应”的确是让人赞叹。不是生物专家，不是文字高手，绝写不出这样的作品。
这本书我喜欢，也希望你们会喜欢！

杨焕明
华大基因理事长
中国科学院院士

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