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Jingdong book

协和风湿免疫病答疑

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协和风湿免疫病答疑

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以问答的形式对风湿免疫病作了详细的介绍。《协和风湿免疫病答疑》作者均为北京协和医院风湿免疫科骨干医师,既具有深厚的风湿免疫性疾病的基础理论知识,又具有丰富的风湿免疫性疾病的诊断与治疗的临床经验,相信《协和风湿免疫病答疑》一定会受到广大医患的欢迎。染发和日光浴是否会诱发风湿免疫性疾病?风湿免疫性疾病分为哪几类?儿童较为常见的风湿免疫性疾病有哪些?老年人常见的风湿免疫性疾病有哪些?风湿免疫性疾病可累及哪些器官和组织?风湿免疫性疾病的常规实验室检查包括哪些?类风湿关节炎的发病机制是什么?类风湿关节炎可产生哪些病理改变?类风湿关节炎有哪些发病类型?类风湿关节炎的临床病程有几种形式?
Content Description

由北京协和医院风湿免疫科主任张奉春教授和张炬教授主编,读者对象为广大非风湿免疫科医生和基层医师,同时也适用于广大的风湿免疫性疾病患者。风湿免疫性疾病常累及多器官、多系统,其发病机制、临床表现及实验室检查结果错综复杂,且临床发病率高。非风湿免疫科的临床医生在诊治与风湿免疫性疫病相关的本科患者的过程中常会遇到诸多问题;且临床就医的大量不同年龄、不同性别及不同民族的风湿免疫性疾病患者也有许多问题希望得到医生的解答。《协和风湿免疫病答疑》作者均为北京协和医院风湿免疫科骨干医师,既具有深厚的风湿免疫性疾病的基础理论知识,又具有丰富的风湿免疫性疾病的诊断与治疗的临床经验,相信《协和风湿免疫病答疑》一定会受到广大医患的欢迎。
Catalogue

第一章风湿免疫性疾病的基本知识
一、免疫系统的组成和功能
1.哪些器官、组织、细胞和分子组成了免疫系统?
2.免疫系统的作用是什么?免疫系统是怎样发挥免疫功能的?
3.什么是抗原和抗体?什么是免疫复合物?
4.什么是免疫球蛋白?免疫球蛋白有什么功能?
5.什么是补体?补体的作用和意义是什么?
6.什么是HLA分子?HLA分子对免疫系统的意义是什么?
7.免疫应答对机体是否都有利?
8.什么是炎症?炎症过程都发生了什么?
9.什么是自身抗体?自身抗体是怎样产生的?
10.什么是自身免疫性疾病?自身抗体在其中起了什么作用?
二、结缔组织的结构和功能
11.什么是结缔组织?结缔组织由哪些成分组成?
12.关节、骨骼和肌肉各由哪些结构组成?
13.正常关节液有哪些成分?
14.血管内皮细胞的功能是什么?
三、风湿免疫性疾病的病因和预防
15.结缔组织病和风湿免疫性疾病是一回事吗?
16.风湿免疫性疾病和免疫损伤有何关系?风湿免疫性疾病的免疫损伤是怎样产生的?
17.哪个年龄段的人群易患风湿免疫性疾病?
18.女性患风湿免疫性疾病的危险较男性高吗?
19.风湿免疫性疾病会遗传吗?遗传因素在风湿免疫性疾病中起多大作用?
20.感染会诱发风湿免疫性疾病吗?
21.周围环境中可能存在哪些致病因素?
22.染发和日光浴是否会诱发风湿免疫性疾病?
第二章风湿免疫性疾病的诊断方法
一、风湿免疫性疾病的分类
23.风湿免疫性疾病分为哪几类?
24.弥漫性结缔组织病包括哪些疾病?
25.儿童较为常见的风湿免疫性疾病有哪些?
26.老年人常见的风湿免疫性疾病有哪些?
27.风湿免疫性疾病可累及哪些器官和组织?
二、风湿免疫性疾病常用的实验室诊断项目
28.风湿免疫性疾病的常规实验室检查包括哪些?
29.血沉和C反应蛋白对风湿免疫性疾病病情有何提示?
30.自身抗体的检测包括哪几类?
31.什么是抗核抗体谱?抗核抗体检测有何意义?
32.什么是抗中性粒细胞胞浆抗体?抗中性粒细胞胞浆抗体怎样分类?各有何意义?
33.人类白细胞抗原检测对风湿免疫性疾病有何意义?
34.风湿免疫性疾病的影像学检查有何价值?
35.超声检查在风湿免疫性疾病中有何意义?
36.何时需行关节穿刺?关节滑液的结果怎样评判?
37.何时需行关节镜检查?关节镜下可以观察到哪些组织的病变?
38.风湿免疫性疾病需要做哪些病理学检查?
三、类风湿关节炎的临床表现与常用诊断方法
39.类风湿关节炎的发病机制是什么?类风湿关节炎可产生哪些病理改变?
40.类风湿关节炎有哪些发病类型?类风湿关节炎的临床病程有几种形式?
41.类风湿关节炎有哪些关节表现?怎样的关节疼痛应受到重视和关注?
42.类风湿关节炎有哪些关节外表现?
43.什么是类风湿结节?出现类风湿结节意味着什么?
44.类风湿关节炎的血清学检查可出现哪些自身抗体?这些自身抗体对早期诊断有意义的是哪些?
……
第三章 风湿免疫性疾病的常用治疗方法
第四章 常见风湿免疫性疾病的治疗建议
第五章 风湿免疫性疾病相关并发症的治疗
第六章 急症的救治
第七章 各种处理对预后的影响
第八章 风湿免疫性疾病患者的护理与保健
附录1 全国风湿免疫性疾病学科地域分布
附录2 常用非甾体类抗炎药物成分表
附录3 常用慢作用药物和细胞毒药物成分表
附录4 常用糖皮质激素制剂比较表
附录5 新型生物制剂表
附录6 高嘌呤含量食物表
Book Abstract

第一章风湿免疫性疾病的基本知识
一、免疫系统的组成和功能
1.哪些器官、组织、细胞和分子组成了免疫系统?
免疫系统由免疫组织、器官、免疫细胞及免疫活性分子等组成。免疫器官根据作用,可分为中枢免疫器官和周围免疫器官。人的胸腺和骨髓属于中枢免疫器官,骨髓是干细胞和B细胞发育分化的场所,胸腺是T细胞发育分化的器官。脾、扁桃体和全身淋巴结等是周围免疫器官,它们是成熟T和B细胞定居的部位,也是发生免疫应答的场所。此外,黏膜免疫系统和皮肤免疫系统也是重要的免疫组织。免疫细胞包括单核巨噬细胞、中性粒细胞、B淋巴细胞、T淋巴细胞、抗原递呈细胞、自然杀伤细胞等。免疫分子包括免疫细胞膜分子,如抗原识别受体、分化抗原、主要组织相容性分子以及一些其他受体分子等;也包括由免疫细胞和非免疫细胞合成和分泌的分子,如免疫球蛋白分子、补体分子以及细胞因子等。
2.免疫系统的作用是什么?免疫系统是怎样发挥免疫功能的?
机体的免疫功能主要表现在三个方面,即免疫预防、免疫稳定和免疫监视。免疫预防指机体抵抗和清除病原微生物或其他异物的功能。免疫预防功能异常可引起疾病,如反应过高可出现超敏反应,反应过低则可导致免疫缺陷病。免疫稳定指机体清除损伤或衰老的细胞,维持其生理平衡的功能。免疫稳定功能失调可导致自身免疫病。免疫监视指机体识别和清除体内出现的突变细胞,防止发生肿瘤的功能。免疫监视功能低下,易患恶性肿瘤。免疫功能通过免疫细胞而完成。免疫系统由淋巴管维持循环,淋巴管广泛分布在除脑以外机体的每一个器官。淋巴管充满白色、黏稠的淋巴液,其中富含脂肪和白细胞。沿淋巴管分布着淋巴结、扁桃体、骨髓、脾、肝、肺、小肠等特殊区域,淋巴细胞在这些特殊区域得到募集、动员并分配到免疫反应的部位。这种精巧的系统结构保证了免疫反应及时而迅速。
Introduction

风湿免疫性疾病是一大类疾病,临床发病率高,可累及各个器官系统,发病机制、临床表现及实验室检查结果错综复杂。其中很多疾病,如系统性红斑狼疮、类风湿关节炎等如不能得到及时正确的诊治,致残率甚至致死率较高。然而风湿免疫学在我国是一门新兴学科,虽然近20余年来在中国从无到有已取得了一定的进步,但经过正规培训合格有经验的风湿免疫病专科医师的数量还远远不能满足广大患者的需求。
我们在临床工作中,经常会很痛心地看到许多患者由于不了解风湿免疫性疾病的基本常识,病急乱投医,听信江湖广告,采用游医偏方,使病情越治越重,给患者本人和家人带来难以承受的痛苦和负担。另一方面,北京协和医院风湿免疫科每天都要超负荷接诊来自全国各地的大量患者,接诊医师在门诊很难有充裕的时间和条件逐个解答每位患者和家属各方面的问题。鉴于以上原因,我们组织编写了这个小册子,所有作者均为北京协和医院风湿免疫科的骨干医师,希望能回答广大风湿免疫性疾病患者的常见问题,提高他们对此类疾病的正确认识;也希望能对广大基层医师和其他专科医师及时正确诊治提供借鉴和帮助。

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Jingdong book